Jinarc 60mg+30mg Tablet 56s

Jinarc 60mg+30mg Tablet is a vasopressin V2-receptor antagonist, with tolvaptan as its active ingredient, used specifically to slow the progression of Autosomal Dominant Polycystic Kidney Disease (ADPKD) in adults. If you're starting this medication, you're probably wondering how the split-dose pack works — it's a 60mg tablet taken in the morning followed by a 30mg tablet taken roughly 8 hours later in the afternoon, and this specific timing helps manage the medication's effect throughout the day. Because tolvaptan increases urine output significantly, you'll likely need to drink considerably more water than usual and have easy access to a bathroom, including overnight. This medication carries a serious safety consideration around liver health, so regular blood tests to monitor liver function are a mandatory, non-negotiable part of treatment, particularly during the first 18 months. Given the intensity of monitoring required and the significant lifestyle adjustment around fluid intake, this is a medication that needs close, ongoing partnership with your nephrologist rather than a "start and forget" approach.

The 60mg (morning) + 30mg (afternoon) split-dose combination represents a titrated maintenance dose in the standard Jinarc dose-escalation regimen for ADPKD, adjusted based on your individual tolerability. Your nephrologist will have guided you through the initial titration steps to reach this dose, and any further adjustments should only be made under their direct supervision.

• Increased thirst
• Significantly increased urination (polyuria), including at night
• Dry mouth
• Fatigue
• Dizziness
• Headache
• Elevated liver enzymes (requires regular monitoring)
• Elevated blood glucose levels
• Elevated uric acid levels or gout
• Signs of liver injury, such as fatigue, loss of appetite, nausea, right upper abdominal discomfort, vomiting, fever, rash, itching, dark urine, or jaundice (uncommon, but requires immediate medical attention)

Store the tablets at room temperature, away from direct sunlight, heat, and moisture, in their original packaging. Keep out of reach of children.

• Take the 60mg tablet in the morning and the 30mg tablet about 8 hours later, exactly as prescribed
• Drink water proactively throughout the day, even before you feel thirsty, and keep water accessible overnight
• Attend every scheduled liver function blood test, especially during the first 18 months of treatment
• Report any signs of possible liver injury (fatigue, nausea, right upper abdominal pain, dark urine, yellowing of the skin or eyes) to your doctor immediately
• Check the expiry date before use
• Store at room temperature, away from heat and moisture
• Keep out of reach of children
• Never stop or adjust your dose without your nephrologist's direct guidance

Swallow each tablet whole with a glass of water, without chewing. Take the 60mg tablet upon waking, followed by the 30mg tablet approximately 8 hours later, and ensure you have ready access to water and a toilet given the significantly increased urination this medication causes.

Jinarc 60mg+30mg Tablet generally has a shelf life of around 2–3 years from the date of manufacture when stored correctly and unopened. Always check the expiry date printed on the blister pack and outer packaging before use.

• Tolvaptan – a selective vasopressin V2-receptor antagonist that reduces cyst cell proliferation and fluid secretion in the kidneys

• Known hypersensitivity to tolvaptan, benzazepine, or benzazepine derivatives
• Elevated liver enzymes or any signs or symptoms of liver injury present before starting treatment, meeting criteria for permanent discontinuation
• Inability to sense or respond to thirst
• Conditions of significant volume depletion
• Hypernatraemia (elevated blood sodium levels)
• Not recommended for use in children or adolescents, as safety and efficacy have not been established in this age group
• Use during pregnancy or breastfeeding is not recommended, given the significant physiological effects of this medication

Tolvaptan levels can be significantly affected by CYP3A inhibitors (such as ketoconazole or certain antibiotics) and inducers, so these combinations require careful dose review with your doctor, and grapefruit juice should generally be avoided. It's essential to inform your nephrologist about every medication you're taking, particularly diuretics and other medications affecting sodium or fluid balance, given tolvaptan's significant effect on water excretion.

Can I order Jinarc 60mg+30mg Tablet online for delivery to Singapore?
Yes, Singapore customers can purchase Jinarc 60mg+30mg Tablet through our online pharmacy, with orders shipped from our Malaysia-based facility.

Do I need a prescription to buy Jinarc 60mg+30mg Tablet?
Yes, Jinarc is a prescription-only medication requiring specialist nephrology oversight, so please check the product listing or reach out to our pharmacist team before ordering.

How long does delivery to Singapore typically take?
Estimated delivery timeframes to Singapore will be shown at checkout based on your address and the shipping option selected.

How can I be sure the product I receive is authentic?
All products sold through our online pharmacy are sourced from authorised suppliers and manufacturers, with each order undergoing quality checks before dispatch.

What pack size is Jinarc 60mg+30mg Tablet available in?
Jinarc 60mg+30mg Tablet is typically supplied as a 28-day split-dose blister pack. Check the product page for current availability and stock status.

Is it safe to order this medication from an online pharmacy instead of buying in-store?
Yes, ordering from a licensed and verified online pharmacy is a safe, regulated way to purchase this product, provided a valid prescription is submitted and the item is stored and shipped under proper conditions.

How should I store the tablets while waiting for delivery or after they arrive?
Keep the tablets at room temperature, away from direct sunlight and heat, and store them in their original packaging once they arrive.

What payment and order tracking options are available for Singapore customers?
Our online pharmacy supports major payment methods and provides order tracking, so you can follow your purchase from checkout through to delivery in Singapore.

Who can I contact if I have questions about my order before or after purchasing, especially regarding continuity of supply?
Our customer support and pharmacist team are available to assist with questions about ordering, delivery, or general product information. Because Jinarc is usually taken on a strict split-dose schedule for ADPKD, consider arranging your reorder in advance so your treatment is not interrupted.